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主营:单克隆抗体、多克隆抗体、重组蛋白,重组多肽,抗体,标记多肽和蛋白质
℡ 4000-520-616
℡ 4000-520-616
rPeptide/Tau-441, (2N4R), P301L mutant/50 µg/T-1014-1
产品编号:T-1014-1
市  场 价:¥6000.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$300.00
品      牌: rPeptide
公      司:rPeptide,Inc.
公司分类:
rPeptide/Tau-441, (2N4R), P301L mutant/50 µg/T-1014-1
商品介绍
Tau is a family of major neuronal microtubule associated proteins that are found in the neurofibrillary tangles (NFT) in Alzheimer"s disease. Tau promotes the assembly and maintains the structure of microtubules in neuronal cells1,2,3. The Tau proteins are derived from alternative mRNA splice variants that originate from a single gene and result in mature proteins that vary in size from 352 to 441 amino acids (36.8 to 45.9 kDa). There are six Tau isoforms, that differ from one another in having three or four microtubule binding repeats (R) of 31-32 amino acids each, and two, one or none amino terminal inserts (N) of 29 amino acids each4. While the fetal brain contains a single isoform of tau (Tau-352) the adult brain has several isoforms all derived from a single gene by alternative mRNA splicing5. Mutations in the Tau gene are known to cosegregate with the disease in frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17)6. Four of the FTDP-17 tau mutations, R406W, V337M, G272V, and P301L, result in tau proteins that are more favorable substrates for phosphorylation by brain protein kinases than the wild-type tau.
品牌介绍

rPeptide是一家生物化学公司,坐落于美国乔治亚州,与雅典毗邻。该公司研发试剂是市场领跑者,主要产品涉及领域为老年性痴呆症与帕金森综合症研究使用的重组蛋白,重组多肽,抗体以及试剂等等。
该公司提供一系列外包服务,从分子生物学,蛋白表达与蛋白纯化到13C与15N 统一标记蛋白与多肽。同时, rPeptide 技术平台可解决可溶性多肽/蛋白(例如:β-淀粉样蛋白、廋蛋白、前胰岛素)在大肠杆菌中表达等历史性难题。

 
 
  rPeptide 主要产品分类  
 

1、Beta淀粉样蛋白
Beta-Amyloid Peptides, Human, Native and Mutant, Recombinant
Beta-Amyloid Peptide Fragments
Beta-Amyloid Labeled Peptides, Recombinant
Beta-Amyloid Labeled Peptides, Synthetic
2、蛋白
Tau
Tubulin
Synuclein
Amyloid Precursor Protein
Apo E
AD/PD related Proteins
Calmodulin
3、标签蛋白
Beta-Amyloid Labeled Peptides, Recombinant
Beta-Amyloid Labeled Peptides, Synthetic
Labeled Calmodulin Proteins
4、单抗
Beta Amyloid
Tubulin
Tau and Related proteins
5、多抗
Tau

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