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产品名称：rPeptide/Human Apolipoprotein E2, Apo-E2/1.0mg/A-2015-4

产品编号：A-2015-4

市场价：¥7200.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>其它重组蛋白>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$360.00

品牌： rPeptide

公司：rPeptide,Inc.

公司分类：

商品介绍

ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE is an important constituent of all plasma lipoproteins. It’s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. E2 allele carriers had significantly lower levels of total cholesterol, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, as well as increased ApoE levels. Recombinant human ApoE2 is a 34.3 kDa protein containing 300 amino acid residues.

品牌介绍

rPeptide是一家生物化学公司，坐落于美国乔治亚州，与雅典毗邻。该公司研发试剂是市场领跑者，主要产品涉及领域为老年性痴呆症与帕金森综合症研究使用的重组蛋白，重组多肽，抗体以及试剂等等。
该公司提供一系列外包服务，从分子生物学，蛋白表达与蛋白纯化到13C与15N 统一标记蛋白与多肽。同时， rPeptide 技术平台可解决可溶性多肽/蛋白（例如：β-淀粉样蛋白、廋蛋白、前胰岛素）在大肠杆菌中表达等历史性难题。

rPeptide 主要产品分类

1、Beta淀粉样蛋白
Beta-Amyloid Peptides, Human, Native and Mutant, Recombinant
Beta-Amyloid Peptide Fragments
Beta-Amyloid Labeled Peptides, Recombinant
Beta-Amyloid Labeled Peptides, Synthetic
2、蛋白
Tau
Tubulin
Synuclein
Amyloid Precursor Protein
Apo E
AD/PD related Proteins
Calmodulin
3、标签蛋白
Beta-Amyloid Labeled Peptides, Recombinant
Beta-Amyloid Labeled Peptides, Synthetic
Labeled Calmodulin Proteins
4、单抗
Beta Amyloid
Tubulin
Tau and Related proteins
5、多抗
Tau